I took the PCAT in March after 6 weeks of first semester chem, 6 weeks of first semester Bio, calculus 10 years prior, and A&P 10 years prior, as well as a year of organic chemistry in high school 11 years prior and did very well. This test is is about test taking ability. Yes, you need the first two semesters of chem and bio to be fully ready, but as someone already said, much of the information can be obtained from a study guide. I suggest going back to refresh your math skills- you know- fractions kind of skills. I did not really study for the exam - I thought I was taking it to find out what the test was like. I walked out thinking that I did poorly, but when I got my score back I was surprised. Most of my friends have been surprised at how easy the test is too.